Musculoskeletal manifestations in hemodialysis patients

نویسندگان

  • Alessandra de Sousa Braz
  • Ângela Luzia B. P. Duarte
چکیده

Uma diversidade de alterações osteoarticulares tem sido descrita em pacientes em hemodiálise crônica. Objetivo: Verificar a proporção e o tipo de manifestação musculoesquelética (MME) nos pacientes em programa de hemodiálise, em três centros da região metropolitana do Recife, e relacionálas com as variáveis sexo, etnia, idade atual do paciente e, ao iniciar a diálise, tempo de tratamento dialítico. Métodos: Inicialmente, foram aplicados questionários em 197 pacientes distribuídos nos três centros no período de março de 2001 a janeiro de 2002. Após excluir 35 pacientes com diagnóstico prévio de doença reumatológica, investigou-se a presença de sinais e/ou sintomas de MME em 162 pacientes. A média de idade foi de 47,3 anos, a média da idade no início do tratamento foi de 43,8 anos, 94 pacientes (58%) eram do sexo masculino e 120 (74,1%), não-caucasóides. O tempo médio do tratamento dialítico foi de 44,1 meses, sendo utilizada a membrana de polissulfona em todos. Resultados: MME foram observadas em 55 (34%) dos 162 pacientes do estudo. Destes, 38 apresentaram um único tipo de manifestação e 17 pacientes, mais de um tipo (16 apresentaram dois e um, três tipos), perfazendo um total de 73 manifestações distribuídas entre articulações (44), ossos (18), estruturas neuromusculares (seis) e periarticulares (cinco). A artralgia foi responsável por 46,6% de todas as MME, e o joelho foi a articulação mais acometida (52,9% dos casos). A dor óssea foi a segunda queixa mais comum (21,9%), as alterações periarticulares corresponderam a 6,8% das MME; e síndrome do túnel do carpo, deformidades ósseas e tumorações articulares ocorreram em 4,1%, 2,7% e 2,7%, respectivamente, do total de MME. Entre os 55 pacientes, alterações articulares foram encontradas em 72,7% deles, ósseas em 32,7%, neuromusculares em 10,8% e periarticulares em 9,1% dos pacientes. Neste estudo, observou-se a relação entre o tempo médio de tratamento dialítico (59,8 meses) e o desenvolvimento de MME (p < 0,001).

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تاریخ انتشار 2004